A woman with big pussy lips - in small clothing looks like she's got a mans package.

Also refers to an ugly vagina. The more beat up the vagina is the more it looks like a mooseknuckle. Loose vagina
Aaron: does yana have a cock?

Rob: naw, shes got some huge coochie flaps aka Mooseknuckle

Aaron: wtfh??

Rob: her shit is loose - beat the fuck up!

Rob: her shit is as big as her forehead

Aaron: word
di Nontoxic 31 marzo 2010
The bump or bulge seen when a man wears tight pants.
"Is that a moose knuckle I see; or do you have a raisin in your pants?"
di the dude1963 20 aprile 2013
The guy version of cameltoe.
Hey... look at that guys, Moose Knuckles... Gross!
di Nastynae 09 giugno 2009
when an obese lady has camel-toe
that camel to is so big its like a moose knuckle
di bob joe's 07 maggio 2012
A male style of a cameltoe
Nick was watching porn and he stood up and has a mooseknuckle
di Tugginmypudda 04 settembre 2010
When a man has a camel toe because he's wearing something really tight.
Mark proudly showed off his huge moose knuckle in his red bike shorts.
di charlesramsey 06 agosto 2013
The broader larger version of a camel toe. Often referring to a woman with a meatier gap from thigh to vulva, also used in accordance with heavy set females.

This term is seemingly being misused for a male equivalent which actually has multiple derivative terms.
Refer to Lobster Claw or Mammal Toe for male definition. Also males bearing the mark from restrictive lower garments are referred to as Grape Smugglers (also just referring to the garment like Ruster or Wrangler jeans).
Citing Seth Rogen and Diana Bangs characters in The Interview

DB: "I particularly enjoyed the Miley Cyrus "Cameltoe" episode, very deep."
SR: "Very deep! Yeah she has quite a hearty moose knuckle!"
di IggyK 24 febbraio 2015

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