Achieve an erection; get a hard-on; by extension, perform any difficult task.
He's so asexual, he couldn't get it up at an Annie Sprinkle marathon.
di Cornholio 04 novembre 2003
to get an erection.
to muster the energy.
Dude, you hear Jack tried to bang his chick last night, but couldn't get it up?

I can't get it up to go shopping today.
di Ptorrens 10 febbraio 2012
when u get an erection or a boner in some senses. also means to not be circumcised or a jew.
i wish my mom would help me getitup but thats just wrong cuz im not getitup.
di xhottbsx 07 marzo 2008

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