2. In other uses (such as gaming), uttered by somebody about to launch what they believe to be an all-out and unstoppable attack against an opponent with the intent of conquering/defeating them in one fell swoop. Only to be used if you want to announce your presence.
3. Also used by a victor just after having utterly crushed an opponent.
2. Player 1: "Well, I've got your forces surrounded. You're going to die now. Resistance is futile"
Player 2: "Oh, we're boned"
3. Spoinkenstein just headshot Cheezsandwich for the 10th time in a row.
Spoinkenstein: Resistance is futile.